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Chunk #26 — Methods — Measurements and data analysis — Measurement issues and solutions — Calculation of spectral coherence variables

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A stable pattern of EEG spectral coherence distinguishes children with autism from neuro-typical controls - a large case control study.
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Spectral coherence was calculated, using a Nicolet™ (Nicolet Biomedical Inc., 5225 Verona Road, Madison, WI 53711 USA) software package, according to the conventions recommended by van Drongelen [30] (pages 143-144, equations 8.40, 8.44). Coherency [45] is the ratio of the cross-spectrum to the square-root of the product of the two auto-spectra and is a complex-valued quantity. Coherence is the square modulus of coherency, taking on a value between 0 and 1. In practice, coherence is typically estimated by averaging over several epochs or frequency bands [30] and in the current project a series of two second epochs were utilized over the total available EEG segments.