The Cilento study is a population-based study that includes 2 137 individuals from three isolated populations of South Italy. Of these individuals, 859 were genotyped on the 370K SNP map from Illumina. Imputation of 2.5M HapMap SNPs was obtained using MACH software. Genome-wide significant SNPs were selected, checked and analyzed. Data available from the NEO-PI-R questionnaire were available for 343 genotyped subjects representing the final sample. Of this sample, 65.6% were women. The mean age of all participants was 58.9 (SD=19), of the men 59.5 (SD=18.8) and of the women 58.7 (SD= 19).