decreased in unadjusted analyses (Table 3) but was stable in adjusted analyses (Table S6). For average volume by birth cohort, among men in the <1925 and 1936–1945 birth cohorts, average volume decreased in unadjusted analyses (Table 4) but remained stable in adjusted analyses (Table S7); among women in the <1925 and 1936–1945 birth cohorts, average volume was stable in unadjusted analyses but increased in adjusted analyses. Results for adjusted quantity and frequency are available (Tables S8 and S9).