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Chunk #17 — 2. Results and Discussion — 2.2. Glx (Complex of Glutamate, Glutamine and GABA)

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Adding Sarcosine to Antipsychotic Treatment in Patients with Stable Schizophrenia Changes the Concentrations of Neuronal and Glial Metabolites in the Left Dorsolateral Prefrontal Cortex.
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Most studies have failed to find any significant correlation between glutamatergic parameters and PANSS score [46,60,66,67,68]. Kegeles et al. report that PANSS positive symptoms subscale scores significantly correlated with levels of GABA and Glx only in MPFC but not in DLPFC [60].