reduce alcohol drinking behaviors, other factors also seem to moderate the protective effect of ADH1B rs1229984 on alcohol drinking behaviors. Two studies conducted in independent samples observed a reduced protective effect of ADH1B rs1229984 on alcohol drinking behaviors in subjects exposed to childhood adversity [Meyers and others 2015; Sartor and others 2014]. A further study observed a reduced protective effect of ADH1B rs1229984 on alcohol drinking behaviors in adolescents reporting most or all best friends drinking [Olfson and others 2014].
