Our analyses of persistent smoking indicate that being a female, smoking the first cigarette at a later age, and having a longer interval between the first and the second cigarette predicts later onset of daily smoking. We detected no genome‐wide significant associations for the transition from the age of smoking the first cigarette to the age when daily smoking started. We likely had insufficient power in the analysis of the binary variable (rapid vs. slow transition) especially when using the mixed effects model. Larger samples are needed to investigate the transition to daily smoking.
