Chunk #39 — Results — Twin studies

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The genetic epidemiology of obsessive-compulsive disorder: a systematic review and meta-analysis.

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yes

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PADUA ABBR––––0.410.390.460.370.350.530.470.44––––0.100.240.110.350.250.250.320.21––––––––––––––––Moore et al. [40]IrelandChildren (12 y)93p161pLOCI-CV0.6780.3000.3610.406Fagnani et al. [41]ItalyAdult (23–24 y)159p180pSCL-900.470.170.451 (0.099–0.586)0.000 (0.000–0.267)0.549 (0.415–0.711)Iervolino et al. [42]UK*TwinsUK adult twin registerAdults women(17–86 y)27201635OCI-R0.47 (0.40–0.53)––0.28 (0.19–0.36)–––0.380 (0.187–0.526)0.090 (0.000–0.252)0.530 (0.472–0.595)Lahey et al. [43]USA*Tennesse Twin StudyAdolescents(6–17 y)Not describedCAPS0.640.320.640 (0.457–0.684)0.000 (0.000–0.166)0.360 (0.316–0.411)Mataix-Cols et al. [7]Sweden*STAGE studyAdults (20–47 y)64719535Clinical interview based on ICD-8,9,10–0.450.49–0.200.120.120.47 (0.40–0.52)0.00 (0.00–0.05)0.53 (0.48–0.58)López-Solà et al. [44]López-Solà et al. [45]Australia*Australian Twin Registry (ATR)Adults (18–45 y)12811214OCI-R0.41 (0.34, 0.48)0.40 (0.27, 0.51)0.42 (0.32, 0.51)0.17 (0.06, 0.26)0.16 (0.03, 0.33)0.23 (0.09, 0.36)0.06 (0.12, 0.23)0.39 (0.18–0.45)0.00 (0.00–0.18)0.61 (0.55–0.68)Mathews et al. [46]Netherlands*NTRAdult1218983PI-ABBR0.400.400.400.200.200.200.200.3760.0220.601Monzani et al. [47]UK*TwinsUK adult twin registerAdult women(16–90 y)30422367OCI-R––0.52––0.21–0.48 (0.42–0.53)–0.52 (0.47–0.58)Zilhão et al. [48]Netherlands*NTRAdult45664714PI-ABBR0.367 (0.327–0.406)0.400 (0.324–0.468)0.359 (0.308–0.400)0.119 (0.867–0.151)0.130 (0.090–0.169)0.084 (0.036–0.131)0.157 (0.083–0.228)–––Krebs et al. [49]UK*TEDSChildren and adolescent (cohort)4 y50727 y52029 y242116 y34979671921641039647ARBQ––––––––––––––––––––––––––––0.59 (0.57–0.61)0.61 (0.57–0.63)0.54 (0.46–0.610.33 (0.26–0.41)0.00 (0.00–0.01)0.02 (0.01–0.04)0.14 (0.09–0.21)0.25 (0.19–0.31)0.41 (0.38–0.43)0.38 (0.36–0.40)0.32 (0.29–0.35)0.42 (0.39–0.45)Pinto et al. [50]Sweden*STAGE studyAdults (19–47 y)836013551Clinical interview based on ICD-8,9,100.48 (0.48–0.52)––0.15 (0.10–0.18)–––0.55–0.63Taylor et al. [51]CanadaAdult (17–81 y)167140OCI-R–––––––0.53–0.47Zilhão et al. [52]Netherlands*NTRAdult39904057PI-ABBR0.3840.3790.3860.1770.1970.1390.2140.373–0.627Taylor et al. [53]Sweden*Child and Adolescent Twin Study (CATS)Child and adolescentNot describedParent-rated A-TAC compulsion module (9 and 12 y); self-rated BOCS (18 y)0.020.02–0.627Burton et al. [54]CanadaAdolescent (6–18 y)60p160pTOCSCBCL-OCS0.74 (0.60–0.83)0.62 (0.44–0.75)––0.37 (0.23–0.50)0.34 (0.20–0.47)–––0.74 (0.63–0.82)0.56 (0.40–0.68)0.26 (0.18–0.37)0.44 (0.32–0.60)MZ monozigotic, DZ dizogotic, MZM monoigotic male, MZF monozygotic female, DZM dizygotic male, DZF dizygotic female, DOS dizygotic opposite sex, HRS-SR Hoarding