Chunk #39 — 4. Discussion — 4.1. Altered Functional Connectivity across Reward Network in AUD Individuals

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Differentiating Individuals with and without Alcohol Use Disorder Using Resting-State fMRI Functional Connectivity of Reward Network, Neuropsychological Performance, and Impulsivity Measures.

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[103], and, therefore, the increased connectivity between pallidum and PCC, may indicate reward related tendencies (e.g., drug seeking) in the resting state. However, despite the growing number of fMRI brain connectivity studies on AUD and other SUDs during resting state and task conditions [19,28,63,94,102,104], more studies are needed to understand the exact role of specific connectivity patterns across the reward network.