Chunk #23 — RESULTS — Neuroimaging Results — Relationship between Connectivity Data and Behavioral Measures

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Resiliency in adolescents at high risk for substance abuse: flexible adaptation via subthalamic nucleus and linkage to drinking and drug use in early adulthood.

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For the entire sample, right STN-right median cingulate connectivity correlated with 0-back RT (r=0.30, p=0.016), but with no other performance measures (p’s>0.169). There were no other correlations between connectivity and substance use or vulnerability measures (p’s>0.077), across the entire sample or within family history/resiliency groups; therefore, these data do not support the hypothesized relationship between connectivity and substance use despite connectivity differences by resiliency group.