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Chunk #25 — Methods — Data structures.

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Single-cell chromatin state analysis with Signac.
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We extended the Seurat Assay class via the R language class inheritance framework to create the ChromatinAssay class for single-cell chromatin data analysis. We extended the Assay class to add slots for the storage of genomic ranges, DNA motifs, genome build information, gene annotations, Tn5 insertion bias, positional enrichment information, genomic links and linked on-disk data storage as fragment files.