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Chunk #37 — MATERNAL CIGARETTE SMOKING DURING PREGNANCY IS ASSOCIATED WITH DIFFERENTIAL miRNA EXPRESSION

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The epigenetics of maternal cigarette smoking during pregnancy and effects on child development.
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partial or imperfect complementarity of a miRNA to a target mRNA can still result in translational repression, a single miRNA has the capability of regulating a number of genes (Du & Zamore, 2007). Through this mechanism of negative regulation, miRNA have been shown to be involved in regulating a number of key biological processes, including cell proliferation, differentiation, and apoptosis, or cell death (Maccani & Knopik, 2012; Maccani & Marsit, 2009; Miska, 2005).