“weighted” strategies respectively. Allelic scores were constructed for BMI, CRP, and LDLc separately. We also constructed allelic scores using 32 variants known to affect BMI [13], 18 variants known to affect CRP levels [14], and 37 variants known to affect LDLc levels [3] (Table S7). These analyses were based on best guess genotypes from imputation using Markov Chain Haplotyping software (MACH v.1.0.16) and phased haplotype data from CEU individuals (Hapmap release 22, Phase II NCBI B36, dbSNP 126) as described previously.
