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Chunk #9 — Materials and methods — Subjects, measurement instruments and genotyping — Discovery samples for personality

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The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data.
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Personality scores were assessed with NEO Personality Inventory–Revised (NEO-PI-R), NEO-PI-3 or the NEO Five-Factor Inventory.2, 40 In each study, scores for the 5 factors N, E, O, A and C were based on the 60 items of the NEO Five-Factor Inventory (12 items per phenotype).2 Summed scores were computed for all five personality dimensions.