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Chunk #1 — 1. Introduction

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Genome-wide association studies of maximum number of drinks.
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on chromosome 4 (LOD = 3.5). Furthermore, Saccone et al. (2005) detected linkage to chromosomes 2 and 7 using a two-stage method. De Andrade et al. (2005) identified suggestive linkage on chromosomes 1, 4, 10 and 13. Linkage for MaxDrinks was also detected on chromosomes 7 (Chen et al., 2005; Saccone et al., 2005). In an Irish affected sib pair study, Kuo et al. (2006) reported that MaxDrinks was associated with regions on chromosomes 12 and 18.