Among RLE subscales (see item composition in Supplementary Table S3) only financial difficulties (RLE-financial) and illness/injury (RLE-illness) had a significant modulating effect in interaction with 5-HTTLPR on the Brief Symptom Inventory depression phenotype (Tables 2–4). The number and frequency of subjects reporting 0, 1, 2 or 3 financial life events and illness/injury-related life events are shown in Supplementary Table S4. To visualise our significant interaction results, we plotted Brief Symptom Inventory depression scores in groups endorsing 0, 1 and 2 or more life events (Figure 1).
