The hypothalamus is an important part of the brain’s stress system (via its connectivity with the amygdala) and is also critical for integrating the CNS with the autonomic nervous system. In addition, the hypothalamus regulates the endocrine system via its connection with the pituitary. The hypothalamus and pituitary are therefore a potential target of some importance for alcohol, and this is a topic of considerable extent that has been reviewed in fine detail elsewhere (Wand, 1999). Here we will quickly review the effect of acute alcohol to regulate vasopressin levels and thereby promote diuresis, another well known biological effect of alcohol that occurs at low to medium levels of the drug.
