Rapid accumulation of new data on human SNPs, knowledge of the complete human genome sequence, and increasing information on biomarcomolecular interactions is opening the way to a more mechanism based understanding of the relationship between genotype and disease. At present, the relevant information is still very incomplete, and is scattered across many databases and thousands of articles. A second primary purpose of the resource is to collect and integrate as much as possible of the molecular level data relevant to the mechanisms that link genetic variation and disease.
