Ethnic-specific residual lipid levels were generated after adjusting for age and gender. Linear regression stratified by self-reported race/ethnicity was used to test the association of residual values with genotype, assuming an additive model of inheritance. To summarize the statistical evidence across the three race/ethnic groups, we conducted a fixed-effects variance-weighted meta-analysis. We computed a weighted average of the beta-coefficient estimates and standard errors (from the linear regression models above) for each genotype, using the inverse of the variance in each group as weights.
