All 453 men were located 10 years later (T10) when 99% completed interviews about their interval substance use and problems, with corroborating data gathered from an additional informant. At the 15-year follow-up (T15), 98% of the original subjects and additional informants were evaluated regarding interval functioning using an interview based on the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) instrument (Bucholz et al., 1994; Schuckit and Smith, 2000). The same data collection methods were used to gather information during the 20, 25, and 30-year follow-ups, with 90% subject retention over the 30 years. Only those probands with DSM-IV (American Psychiatric Association, 1994) alcohol abuse or dependence at T10 (age ~30 years) were included these analyses (n=129), representing 28.7% of the 450 subjects evaluated at the 10-year followup.
