In order to confirm the consistency of the genotypes from the GWA analyses, we performed simultaneous regenotyping of the selected eight variants both in the CRIME sample as well as in the GenMets controls from Health2000 (Genmets sample) by another technology (Sequenom MassARRAY iPLEX). There was a >99% similarity between the original genotypes from GWAS in the discovery analysis and in the regenotyping (Supplementary Information). Thus, the original signals from the GWAS on 6p21.2 and 6p21.32 were not due to spurious genotyping errors.
