Chunk #20 — Results — Unaltered mRNAs expression of glutamate and GABA-A receptor subunits in the putamen of alcoholics

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GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics.

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We then examined the expression levels between controls and alcoholics. No significant difference was detected in mRNAs expression levels for any of the glutamate subunits (Figure 6) nor for any GABA-A receptor subunits between the two groups (Figure 8) in the putamen. Age, brain pH, PMI, smoking history, or RQI did not alter the significance between the two groups.