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Chunk #29 — Introduction — Genome-wide association studies (GWAS)

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The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.
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The ADNI work analyzed a publicly available dataset (adni.loni.usc.edu) for which MRI scans and GWAS data could be freely downloaded from approximately 800 people. The ease of access of the ADNI data, and the principle of broad dissemination of the genomic data with fairly few restrictions led to over 100 genetic studies of the ADNI data, many of them using GWAS designs (Saykin et al. 2010).