in terms of neural communication in both healthy subjects and patients with various neurological and psychiatric [24,26,27] and substance use disorders (SUD) [28,29], including AUD [30,31,32,33,34,35,36]. However, to our knowledge, there have been no studies exploring both cortical and subcortical reward networks during resting state in abstinent individuals with past history of AUD, and who manifest a variety of neurocognitive deficits [37]. Since studying detoxified and abstinent AUD individuals relative to healthy controls without past AUD has an advantage in determining the brain impacts due to chronic past drinking without the confounding effects of current drinking [8,38,39], the current study provides an important opportunity to investigate the resting-state functional connectivity of the reward network in abstinent individuals with past AUD.
