paperKB
coga / coga-kb
Help
Sign in

Chunk #53 — ONLINE METHODS — Multiple-tissue validation results

Source
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.
Embedded
yes

Text

category in the Roadmap dataset. We hypothesize that the lung samples analyzed in GTEx may have contained substantial amounts of blood and thus exhibited a gene expression signature reflecting immune activity; this is supported by a GO enrichment analysis of the lung gene set, in which the top three results were related to antigen presentation, immune response, and cytokine-mediated signaling, respectively.