Chunk #30 — Introduction — Mouse models of CLL — MiR-29 driven mouse model of CLL
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serum of miR-29 mice and wild type littermates. We showed that in miR-29 transgenics immune response to SRBC antigen and serum levels of immunoglobulins were significantly decreased [55]. Thus, these findings confirmed our initial observations that miR-29 transgenics develop a disease mimicking the indolent human counterpart.