paperKB
coga / coga-kb
Help
Sign in

Chunk #24 — ACUTE EFFECTS OF ALCOHOL ON THE BRAIN IN SOCIAL DRINKERS — Acute effects of alcohol on ERPs

Source
Understanding alcohol use disorders with neuroelectrophysiology.
Embedded
yes

Text

This has been studied with a “reverse oddball” Go/NoGo task, a paradigm widely used to estimate response inhibition (Jodo and Kayama, 1992; Eimer, 1993; Falkenstein et al., 1999) wherein a subject has to respond to a given stimulus (Go) and withhold it for another stimulus (NoGo). The ERPs to the two stimuli were examined to evaluate the neural correlates of response production and inhibition. Two significant ERP signatures of response inhibition have been found: an enlarged negative frontocentral N2 component (200–300 ms) on NoGo trials, and an augmented positive-going frontocentral “NoGo P3” (300–600 ms) (Pfefferbaum et al., 1985; Pfefferbaum and Ford, 1988; Eimer, 1993; Filipovic et al., 1999).