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Chunk #35 — Results — Resolving Neuron Types within the Basal Ganglia

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Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain.
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To define GPe neuron types, we screened markers of global clusters and subclusters for expression in the GPe (GP/NB dataset). GPe neurons were present in cluster 2 (n=11,103 cells), one of three neuron clusters (Figure 6A). Cluster 1 contained cholinergic neurons (n=437 cells) and cluster 3 contained neurons of the adjacent striatum and basolateral amygdala (n=9,847 cells). Within cluster 2, 8 of 25 subclusters appeared intrinsic to the GPe or adjacent ventral pallidum (VP), of which 4 were GPe-exclusive (Figure 6B–E). The other 17 subclusters mapped to the thalamic reticular nucleus, the substantia innominata, and the lateral olfactory tract (Figure S6A–D).