To determine if our findings were robust–reproducible across datasets–we repeated our entire analysis on a second resting-state fMRI dataset (rest2 scans) acquired from the same set of subjects. Results were consistent with previous analysis (performed on data from rest1 scan): (i) Functional brain connectivity and small-world metrics including the global efficiency were salient in the low frequency interval–0.01 to 0.05 Hz (Scale 3), (ii)No significant differences in the mean λ values were observed, (iii) Mean γ values in the AD group were significantly lower than in the control group (p<0.01), (iv) Mean σ values in the AD group were significantly lower than that in the control group (p<0.01), (v) No significant differences in the mean Eglobal values were observed, and (vi) significantly lower clustering coefficient values were found in the left and right hippocampus in AD, with no significant differences in the left and right precentral gyrus.
