Alcohol use disorder (AUD) and related health conditions result from a complex interaction of genetic, neural and environmental factors, with differential impacts across the lifespan. 1 , 2 , 3 , 4 The Collaborative Study on the Genetics of Alcoholism (COGA) is a multi‐site, interdisciplinary study that uses a family‐based research strategy focused on families densely affected with AUD and community comparison families. The goal of COGA is to elucidate the genetic and molecular mechanisms underlying the predisposition for AUD, uncovering neurobiological processes that potentially mediate genetic influences, and characterizing the interplay of genetic and environmental risk factors. 1 Briefly, multi‐modal data has been collected on family members (aged 7–97), including clinical and behavioral measures derived from an age‐tailored version of the Semi Structured Assessment for the Genetics of Alcoholism (SSAGA; see 1. Overview), various questionnaires on behavior, personality and social functioning, blood samples for genetic analyses, and a neuropsychological and neurophysiological battery to assess brain function (see 2. Sample and Clinical Data). Data were collected at seven study sites across the United States, each lab operating under the same
