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Chunk #50 — Materials and Methods — Imputation of genetic data

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Bayesian test for colocalisation between pairs of genetic association studies using summary statistics.
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Quality control filters were applied both before and after imputation. Before imputation, individuals with more than 10% missing genotypes were removed, and SNPs showing a missing rate greater than 10%, a deviation for HWE at a p-value less than 0.001 were dropped. After imputation, monomorphic SNPs were excluded from analyses.