Chunk #23 — Results — The Power of GWAS Using Commercially Available Chips

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Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip.

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We simulated putative disease loci at SNPs in phase II of the HapMap within twenty-two one megabase regions on each of the autosomes, a total of nearly 50,000 SNPs, which together are typical for the genome in terms of SNP coverage and recombination rates (see Figure S5 and Text S1 for details).