and between the five predominant immunologic families in the PFC-based putative microglia module. To generate this roadmap to the complex structure of the immune/microglia module, genes which were not direct members of one of these five core pathways were assigned to the family with which they have the greatest number of causal interactions. The immune module was dissected into five families representing functional immune pathways that were labeled according to their main function as ‘Complement’, ‘Fc’ for Fc-receptors, ‘MHC’ for major histocompatibility complex, ‘Cytokines’ for cytokines/chemokines and ‘Toll-like’ for toll-like receptors (Figure 5).
