Risk for the transition from initiating to the emergence of problem substance use in adolescence is influenced by a variety of factors. For example, youth who exhibit susceptibility cognitions (intentions to use or curiosity about drugs) (Pierce et al., 1996) are twice as likely than youth who do not see substance use this way to start smoking cigarettes during adolescence (Choi et al., 2001; Nodora et al., 2014; Strong et al., 2015). Recent research suggests that risk may extend to other tobacco products as well (Trinidad et al., 2018). In addition, parenting, home environment, neighborhood factors such as alcohol and drug availability, and peer influence have all been shown to impact substance use onset and outcomes (Buu et al., 2009; Curran et al., 1997; Dielman et al., 1993; Marshal et al., 2003; Trentacosta et al., 2009). The Culture and Environment module of the ABCD protocol covers many of these potential influences on substance use, including parental monitoring, family environment and conflict, and neighborhood safety and crime. In addition to these domains, the ABCD substance use module captures low level substance