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Chunk #7 — THE GENETIC BASIS OF VULNERABILITY TO ALCOHOLISM

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Genetic influences on the development of alcoholism.
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Genetic vulnerability to alcoholism may originate in personality traits (such as anxious, dysphoric temperament and impulsivity) that predispose to alcohol seeking behavior, differential response to the effects of alcohol or differential variation in the neurobiology underlying addiction and physiological response to stress. Although alcoholism is often comorbid with other psychiatric disorders the heritability is largely disease specific [1]. The exception is nicotine addiction with which there is a strong genetic correlation [1].