The present comorbidity profiles are largely consistent with LCA results obtained from other cohorts (Olino et al., 2012; Vaidyanathan et al., 2011) and from our prior modeling of comorbidity from the 1992 diagnostic interview in the full sample of male twins from the VETR (from which our twin families were a subset), in which we found a profile consisting of alcohol and nicotine dependence, a second consisting of mood and anxiety disorders, and a third with high probability of externalizing disorders and illicit drug dependence (Todorov et al., 2006).
