Chunk #18 — 3. Results — 3.2 Allelic Imbalance assay

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Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex.

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Figure 1 illustrates ASE of ZNF804A at the expressed SNP rs12476147 in the DLPFC. A non-significant over-expression of the rs12476147 A allele was detected in cDNA A/T allele ratios compared to A/T allele ratios of rs12476147 observed in genomic DNA (average 1.03, 95% CI 1.00-1.06; p-value < 0.12, after correction for genomic DNA A/T assay).