of the recorded active cells yet they are more informative about the behavioral outcome than the entire remaining population (Ferbinteanu and Shapiro, 2003; Frank et al., 2000; Fujisawa et al., 2008; Pastalkova et al., 2008; Quian Quirroga et al., 2005; Wood et al. 2000). In the olfactory bulb, less than 10% of sharply tuned reader-classifier mitral cells are responsible for generating discrete and defined outputs, even though a large fraction of neurons contribute some spikes (Niessing and Friedrich, 2010).