As it has been one of the goals of genetical genomics to identify biological relationships we suggest that the conditioned co-expression analysis we carried out here, might help to uncover these: We have shown that more known biological relationships can be identified when using genetical genomics to perform co-expression analyses that have been conditioned on genotype. An explanation for this observation is that cis-eQTLs sometimes convolute co-expression, as is exemplified for UBA52, where primer polymorphisms probably affect hybridization characteristics.
