With the increased deployment of systems genetics and the availability of high-throughput molecular phenotypes in the newly expanded BXD RI strain population, there is a tremendous need for expanded complementary behavioral phenotyping in these strains. Using the high-throughput behavioral phenotyping cores established by the NIMH ENU-Neuromutagenesis Program of the TMGC, we have characterized 257 behavioral measures in the BXD RI lines. All of the primary data, strain means and candidate gene sets have been made publicly available in MouseTrack, GeneNetwork and the ODE. The availability of data that spans multiple phenotypes covering diverse aspects of behavior is intended to populate regions of sparse information within the existing BXD RI phenome, which we anticipate will be useful to future systems genetic analysis of brain and behavior.
