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Chunk #18 — Results — Single variant (GWAS and meta-analyses), gene and pathway analyses

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Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability.
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No variants achieved genome-wide significance in either the transethnic or EA meta-analyses. For Manhattan plots, QQ plots and top hits tables for each of the three meta-analyses, see Supplementary Figures S1 and S2 and Supplementary Tables S3–S5. Though not currently informative about individual risk loci, summary statistics are useful for polygenic predictions and cross-disorder analyses, and are available for download: www.med.unc.edu/pgc.