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Chunk #70 — II. Samples for genome studies of human addiction vulnerabilities and related phenotypes (Figure 2)

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Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects.
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N. Sample 14) European American smokers who successfully vs unsuccessfully quit smoking in trials in Rhode Island: Participants engaged in a ten week, double-blind placebo controlled trial of placebo or bupropion (150 mg/day for the first 3 days, then 300 mg/day) with a target quit date one week following initiation of drug or placebo [119]. Sixty individuals with biochemically-confirmed abstinence for at least the 7 days prior to both the end of treatment and 24 week assessments were contrasted with 90 unsuccessful quitters who were not abstinent at either time point.