The variation across individuals within T-cells (median 33.2%) and monocytes (median 16.4%) is substantially larger than when the two cell types were combined (Fig. 4 h). The fact that the contribution of individual varies between cell types is consistent with cell-specific regulatory genetics [1]. Finally, the fraction of variation explained by individual within each cell type at the gene-level is directly related to the probability of each gene having cis-eQTL within the corresponding cell type (Fig. 4 i).
