full Caucasian CMC cohort was: adjusted gene expresion~SNP dosage+5 ancestry vectors+Dx FDR was estimated separately for cis-eQTL (defined as ≤ 1 MB between SNP marker and gene position) and trans-eQTL (> 1 MB between marker and gene), controlling for FDR one chromosome at a time. The regression modeling was performed for SNPs on the X chromosome in the same manner as for those on the autosomes (i.e., with a dosage scaling between 0 and 2 for both males and females); this gender-neutral model was appropriate here since the gene expression was already adjusted for gender.
