paperKB
coga / coga-kb
Processing
Help
Sign in

Chunk #20 — Results — Genetic correlations — PTSD-Alcohol-related Problems

Source
Differences in genetic correlations between posttraumatic stress disorder and alcohol-related problems phenotypes compared to alcohol consumption-related phenotypes.
Embedded
yes

Text

Notably, the rG between all PTSD phenotypes and alcohol-related problems phenotypes are positive for EA individuals (rGs: 0.132–0.533, all FDR adjusted p < 0.05). The rG estimates for PTSD with Max. Alc., AUDIT-P, AUD and AD phenotypes were positive and moderate (rGs: 0.289–0.533, all FDR adj. p < 0.01) with the exception of AUDIT-P and PTSD Re-Exp, which was small, still positive (rG: 0.132, FDR adj. p = 0.044). All these rG estimates passed FDR adjustment. Notably, the highest rG were between the two PTSD phenotypes and AD (rG: 0.472–0.533, p < 0.001).