Using Gene Ontology (GO) enrichment [11], we found the target genes of these expression associated CNVs (eCNVs) to show a highly significant overrepresentation for certain biological processes including immune response (p = 2.3e-4, adjusted p-value 0.034) and regulation of apoptosis (p = 8e-6, adjusted p-value 0.015). Relative to other genic CNVs, the observation on the enrichment of the target genes of eCNVs for response to stimuli continues to hold (p = 9.9e-3, adjusted p-value 0.05).
