use behaviors31,90 have not, however, found variants in this region of chromosome 18 to be genome-wide significant. In addition, it will be important for future work to combine the advantages of the superior spatial resolution of MRI and the superior temporal resolution of EEG to better understand functional connectivity. Finally, future studies should examine how findings from this work could potentially translate into useful targets for neurofeedback among individuals with AUD, and those at risk, given the success of neurofeedback as a therapeutic tool, alongside other behavioral and pharmacological therapies91.