As examples of association trajectories, Figure 2 shows genotypic effects of 4 cholinergic SNPs on frontal auditory ERO trajectories from the regression model in rows 1 and 3, shows how mean phenotypic trajectories vary by genotype. These lines should be compared to the blue lines (FZ electrode) in the top left panel of Figure 1 to see the allelic split compared to the overall mean. The corresponding association trajectories of the SNPs, expressed in standard deviations of the data, are shown in rows 2 and 4. The large separation between the lines in rows 1 and 3 corresponds to the enhanced colors in rows 2 and 4. Note the opposite effect sizes for males and females for the nicotinic receptor SNPs, particularly the CHRNA3 SNP.
