In model 2, the genetic and environmental pathways a3,1, c3,1 and e3,1 in Figure 2 are removed. In this model, none of the association between availability and abuse is due to latent, correlated liabilities stemming directly from A1, C1 and E1 via a3,1, c3,1 and e3,1 to the abuse phenotype. Rather, any association between availability and the diagnostic measures is mediated entirely via initiation through path β2 at the phenotypic level.
