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Chunk #54 — DISCUSSION — ERO and PLI analyses in HAP-1, LAP-1 and HS/Ibg mice

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Event-related oscillations as risk markers in genetic mouse models of high alcohol preference.
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greater in HAP-1 mice than in LAP-1 and HS/Ibg mice (Slawecki et al., 2003). In contrast, the present study found that HAP-1, LAP-1 and HS/Ibg mice showed no significant differences in ERO energy in the delta, theta and alpha/beta bands in the 0 to 50 ms time window. However, we found that HAP-1 mice showed higher theta ERO energy than LAP-1 mice in the 50–350 ms time window, in response to rare tones. In contrast, HAP-1 and LAP-1 mice showed no significant differences in theta PLI. Differences in P1 amplitude between HAP-1 and LAP-1 mice were observed in all three tones (Slawecki et al., 2003), whereas differences in theta ERO energy between HAP-1 and LAP-1 were only observed in response to rare tones.