Probands, siblings and parents were interviewed by clinically-trained research interviewers, most of whom had extensive clinical experience with alcoholism. The assessment included demographic characteristics, lifetime history of AD and other comorbid conditions, alcohol-related traits, personality features, and clinical records. The DSM-IV AD diagnosis was assessed in probands and siblings using the modified Semi-Structured Assessment of the Genetics of Alcoholism (SSAGA) version 11 17 interview to reduce assessment time.
